The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is preferentially expressed in mature B lymphocytes, and may be important for B cell development and autoimmune response. This receptor has been shown to specifically bind to the tumor necrosis factor (ligand) superfamily, member 13b (TNFSF13B/TALL-1/BAFF), and to lead to NF-kappaB and MAPK8/JNK activation. This receptor also binds to various TRAF family members, and thus may transduce signals for cell survival and proliferation
Immunogen Information
Immunogen
Synthetic peptide of human TNFRSF17
Swissprot
Q02223
Synonyms
B cell maturation antigenB cell maturation factorB cell maturation proteinB-cell maturation proteinBCMBCMACD269CD269 antigenTNFRSF17TNR17Tumor necrosis factor receptor superfamily member 17