CAV1 Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
Product Name
CAV1 Polyclonal Antibody
Catalog Number
RD70891A
Clonality
Polyclonal
Purification Method
Affinity purification
Isotype
IgG
Host
Background
May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity (By similarity). Involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation. Its binding to DPP4 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependent manner. Recruits CTNNB1 to caveolar membranes and may regulate CTNNB1-mediated signaling through the Wnt pathway.
Immunogen Information
Immunogen
Synthesized peptide derived from the C-terminal region of human Caveolin-1
Swissprot
Q03135
Synonyms
BSCL3CAVCAV1CAV1caveolae protein22 kDcaveolin 1 alpha isoformcaveolin 1 beta isoformCaveolin 1 caveolae protein 22kDaCaveolin-1Caveolin1cell growth-inhibiting protein 32CGL3LCCNSMSTP085OTTHUMP00000025031PPH3VIP 21VIP21
Calculated MW
20 kDa
Observed MW
25 kDa
Applications
Conjugation
Unconjugated
Dilution
WB 1:500-2000, IHC 1:50-300, IF 1:50-300
Concentration
1 mg/mL
Storage Buffer
PBS with 0.02% sodium azide, 0.5% protective protein and 50% glycerol, pH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.