CASP8 Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
Product Name
CASP8 Polyclonal Antibody
Catalog Number
RD219664A
Clonality
Polyclonal
Purification Method
Antigen affinity purification
Isotype
IgG
Host
Background
Caspase 8,also named as MCH5,MACH,FLICE,and CAP4,belongs to the peptidase C14A family. It may participate in the GZMB apoptotic pathways and functions as an upstream regulator in a-bisabolol-induced apoptosis. Caspase 8 catalyzes an essential intermediate step in the ubiquitination and proteasome-mediated degradation of IRF3. It may control diabetic embryopathy-associated apoptosis via Caspase 8 is expressed as nine isoforms by alternative splicing with the molecular mass from 26 kDa to 62 kDa. Caspase 8 Monoclonal Antibody can recognize pro- and cleaved-caspase 8.
Immunogen Information
Immunogen
Synthetic peptide of human CASP8
Swissprot
Q14790
Synonyms
ALPS2BAmyotrophic lateral sclerosis 2 chromosomal region candidate gene 12 proteinApoptotic cysteine proteaseApoptotic protease Mch-5Apoptotic protease Mch5CAP4CASP-8CASP8CASP8Caspase 8Caspase 8 apoptosis related cysteine peptidaseCaspase-8 sub
Gene Accession
NP203519
Applications
Research Areas