This gene encodes a protein involved in regulation of the cell cycle through interactions with several cyclin-dependent kinases. One study (PMID: 16177568) reported aberrant splicing of transcripts from this gene which results in removal of the cyclin binding domain only in human cancer cells, and reduction in gene expression was shown in colorectal cancers (PMID: 17982127).Multiple transcript variants encoding different isoforms have been found for this gene.
Immunogen Information
Immunogen
Recombinant protein of human CABLES1
Swissprot
Q8TDN4
Synonyms
CABL1CABLESCables1Cdk5 and Abl enzyme substrate 1CDK5 and ABL1 enzyme substrate 1FLJ35924HsT2563IK3 1Ik3-1Interactor with CDK3 1