BCAS4 Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
Product Name
BCAS4 Polyclonal Antibody
Catalog Number
RD78925A
Clonality
Polyclonal
Purification Method
Affinity purification
Isotype
IgG
Host
Background
The gene encoding BCAS4 (Breast carcinoma-amplified sequence 4), a 211 amino acid protein, is found in a region on chromosome 20 that is frequently amplified in human breast cancer.The amplification and translocation between the BCAS4 gene and the BCAS3 gene, with a 17q23 locus, results in a fusion transcript that is overexpressed in MCF-7 cells. Also, deletion of chromosomal region 20q13.13-q13.2 and resultant deletion of BCAS4, as well as three other genes, is the cause of Okihiro syndrome, a disease characterized by ocular and upper limb anomalies.
Immunogen Information
Immunogen
Synthetic peptide of human BCAS4
Swissprot
Q8TDM0
Synonyms
BCAS4BCAS4/BCAS3 fusionBCAS4Breast carcinoma amplified sequence 4Breast carcinoma amplified sequence 4/3 fusion proteinBreast carcinoma-amplified sequence 4CNOLFLJ20495RP5-1071L10.2
Calculated MW
23 kDa
Gene Accession
NP_001010974
Applications
Research Areas