Accelerates programmed cell death by binding to, and antagonizing the apoptosis repressor BCL2 or its adenovirus homolog E1B 19k protein. Under stress conditions, undergoes a conformation change that causes translocation to the mitochondrion membrane, leading to the release of cytochrome c that then triggers apoptosis. Promotes activation of CASP3, and thereby apoptosis.
Immunogen Information
Immunogen
Synthetic Peptide of Bax
Swissprot
Q07812
Synonyms
Apoptosis regulator BAXBAXBax-proteinBAXBAXABaxdelta2G9Baxdelta2G9omegaBaxdelta2omegaBcl-2-like protein 4BCL2 associated X proteinBCL2 associated X protein omegaBCL2 associated X protein transcript variant delta2Bcl2-L-4BCL2L4membrane isofor