BAG2 Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
Product Name
BAG2 Polyclonal Antibody
Catalog Number
RD219397A
Clonality
Polyclonal
Purification Method
Antigen affinity purification
Isotype
IgG
Host
Background
BAG proteins compete with Hip for binding to the Hsc70/Hsp70 ATPase domain and promote substrate release. All the BAG proteins have an approximately 45-amino acid BAG domain near the C terminus but differ markedly in their N-terminal regions. The predicted BAG2 protein contains 211 amino acids. The BAG domains of BAG1, BAG2, and BAG3 interact specifically with the Hsc70 ATPase domain in vitro and in mammalian cells. All 3 proteins bind with high affinity to the ATPase domain of Hsc70 and inhibit its chaperone activity in a Hip-repressible manner.
Immunogen Information
Immunogen
Synthetic peptide of human BAG2
Swissprot
O95816
Synonyms
BAG 2BAG family molecular chaperone regulator 2BAG-2BAG-family molecular chaperone regulator-2Bag2BAG2BCL 2 associated athanogene 2Bcl-2-associated athanogene 2BCL2 associated athanogene 2BCL2-associated athanogene 2dJ417I1.2 (BAG family molecul
Calculated MW
24 kDa
Observed MW
Refer to figures
Gene Accession
NP004273
Applications
Research Areas