ATXN7L3 Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
Product Name
ATXN7L3 Polyclonal Antibody
Catalog Number
RD218358A
Clonality
Polyclonal
Purification Method
Antigen affinity purification
Isotype
IgG
Host
Background
Component of the transcription regulatory histone acetylation (HAT) complex SAGA, a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates in a subcomplex that specifically deubiquitinates both histones H2A and H2B. The SAGA complex is recruited to specific gene promoters by activators such as MYC, where it is required for transcription. Required for nuclear receptor-mediated transactivation. Within the complex, it is required to recruit USP22 and ENY2 into the SAGA complex.
Immunogen Information
Immunogen
Fusion protein of human ATXN7L3
Swissprot
Q14CW9
Synonyms
AT7L3Ataxin 7 like 3Ataxin 7 like protein 3Ataxin-7-like protein 3atxn7l3SAGA associated factor 11 homologSAGA-associated factor 11 homolog
Gene Accession
BC113595
Applications
Research Areas