ATF6B Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
Product Name
ATF6B Polyclonal Antibody
Catalog Number
RD218330A
Clonality
Polyclonal
Purification Method
Antigen affinity purification
Isotype
IgG
Host
Background
The protein encoded by this gene is a transcription factor in the unfolded protein response (UPR) pathway during ER stress. Either as a homodimer or as a heterodimer with ATF6-alpha, the encoded protein binds to the ER stress response element, interacting with nuclear transcription factor Y to activate UPR target genes. The protein is normally found in the membrane of the endoplasmic reticulum; however, under ER stress, the N-terminal cytoplasmic domain is cleaved from the rest of the protein and translocates to the nucleus. Two transcript variants encoding different isoforms have been found for this gene.
Immunogen Information
Immunogen
Fusion protein of human ATF6B
Swissprot
Q99941
Synonyms
ATF6BCREBL1G13Cyclic AMP-dependent transcription factor ATF-6 betacAMP-dependent transcription factor ATF-6 betaActivating transcription factor 6 betaATF6-betaProtein G13cAMP response element-binding protein-related protein;
Calculated MW
77 kDa
Observed MW
Refer to figures
Gene Accession
BC008394
Applications
Research Areas