ASNA1 Polyclonal Antibody

For reference only. Please follow the manual included in your kit for instructions.

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Overview

Circle
Product Name
ASNA1 Polyclonal Antibody
Catalog Number
RD253162A
Clonality
Polyclonal
Purification Method
Antigen affinity purification
Isotype
IgG

Background

Circle
ASNA1 (also known as TRC40) is a highly conserved ATPase involved in efflux of arsenite and antimonite. Reduced ASNA1 expression is associated with significant inhibition of cell growth,increased apoptosis and increased sensitivity to cisplatin and arsenite.Thus ASNA1 is proposed to be a target to overcome resistance to cancer chemotherapy. In addition,ASNA1 has been identified as an ER targeting factor for tail-anchored proteins in the posttranslational membrane insertion pathway.

Immunogen Information

Circle
Immunogen
Fusion protein of human ASNA1
Swissprot
O43681
Synonyms
ARSA 1ARSAArsA arsenite transporter ATP binding homolog 1ArsA arsenite transporterATP bindingE. colihomolog of1ArsA arsenite transporterATP-bindinghomolog 1 (bacterial)ARSA IARSA-IARSA1ARSAIArsenical pump driving ATPaseArsenical pump-drivi
Gene Accession
BC002651

Applications

Circle
Reactivity
Tested Applications
Conjugation
Unconjugated
Dilution
IHC 1:50-1:200, ELISA 1:5000-1:10000
Concentration
1.26 mg/mL
Storage Buffer
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.

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