AKR1C1 Polyclonal Antibody

For reference only. Please follow the manual included in your kit for instructions.

Catalog Number
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Overview

Circle
Product Name
AKR1C1 Polyclonal Antibody
Catalog Number
RD76456A
Clonality
Polyclonal
Purification Method
Affinity purification
Isotype
IgG

Background

Circle
This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols by utilizing NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme catalyzes the reaction of progesterone to the inactive form 20-alpha-hydroxy-progesterone. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14.

Immunogen Information

Circle
Immunogen
Synthetic peptide of human AKR1C1
Swissprot
Q04828
Synonyms
2-dihydrobenzene-12-diol dehydrogenase20 alpha (3 alpha) hydroxysteroid dehydrogenase20 ALPHA HSD20 alpha hydroxysteroid dehydrogenase20-alpha-HSD20-alpha-hydroxysteroid dehydrogenase20ALPHAHSD2ALPHAHSDAK1C1AK1C1AKR1C1Aldo keto reductase famil
Calculated MW
37 kDa
Gene Accession
NP_001344

Applications

Circle
Reactivity
Tested Applications
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000, IHC 1:50-1:200
Concentration
0.2 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.

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