AIF1 Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
Product Name
AIF1 Polyclonal Antibody
Catalog Number
RD75217A
Clonality
Polyclonal
Purification Method
Affinity purification
Isotype
IgG
Host
Background
This gene is induced by cytokines and interferon. Its protein product is thought to be involved in negative regulation of growth of vascular smooth muscle cells, which contributes to the anti-inflammatory response to vessel wall trauma. Three transcript variants encoding different isoforms have been found for this gene.Actin-binding protein that enhances membrane ruffling and RAC activation. Enhances the actin-bundling activity of LCP1. Binds calcium. Plays a role in RAC signaling and in phagocytosis. May play a role in macrophage activation and function. Promotes the proliferation of vascular smooth muscle cells and of T-lymphocytes. Enhances lymphocyte migration. Plays a role in vascular inflammation.
Immunogen Information
Immunogen
Recombinant protein of human AIF1
Swissprot
P55008
Synonyms
AIF 1AIF-1Aif1AIF1 proteinAIF1Allograft inflammatory factor 1Allograft inflammatory factor 1 splice variant Gallograft inflammatory factor-1 splice variant Hara-1balloon angioplasty responsive transcriptionBART 1G1G1 putative splice variant of
Calculated MW
17 kDa
Gene Accession
BC009474
Applications
Research Areas