ACVR1 Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
Product Name
ACVR1 Polyclonal Antibody
Catalog Number
RD77840A
Clonality
Polyclonal
Purification Method
Affinity purification
Isotype
IgG
Host
Background
Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I ( I and IB) and two type II (II and IIB) receptors. These receptors are all transmembrane proteins, composed of a ligand-binding extracellular domain with cysteine-rich region, a transmembrane domain, and a cytoplasmic domain with predicted serine/threonine specificity. Type I receptors are essential for signaling; and type II receptors are required for binding ligands and for expression of type I receptors.
Immunogen Information
Immunogen
Recombinant protein of human ACVR1
Swissprot
Q04771
Synonyms
Activin A receptor type IActivin A receptor type II like kinase 2Activin receptor type IActivin receptor type-1Activin receptor-like kinase 2ACTR-IACTRIAcvr1ACVR1ACVR1AACVRLK2ALK 2ALK-2ALK2FOPHydroxyalkyl protein kinaseSerine/threonine-pro
Gene Accession
BC033867
Applications